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A migraine headache is a form of vascular headache. Migraine headache is caused by vasodilatation (enlargement of blood vessels) that causes the release of chemicals from nerve fibers that coil around the large arteries of the brain. Enlargement of these blood vessels stretches the nerves that coil around them and causes the nerves to release chemicals. The chemicals cause inflammation, pain, and further enlargement of the artery. The increasing enlargement of the arteries magnifies the pain.

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A bruise can sometimes be associated with a temporary raised area in the skin. When a bruise fades, it becomes green and brown as the body metabolizes the blood cells and bilirubin pigment in the skin. A bruise is best treated with local application of a cold pack immediately after injury.

It is often throbbing and stabbing because each time the heart pumps blood into the artery, there is an expansion of the artery which aggravates the pain. When the heart rests, the artery partially constricts resulting in a relief of pain.

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